Reading science fictions over the past one hundred years, one sees many seemingly impossible machines and services, which are now not only widely available, but have become accepted as natural. In this talk, Dr. Hsiao-Wuen Hon will share examples which show how technologies developed in research labs have impacted real life user experiences. For example, body gesture, speech, natural user intent understanding, and other new usage scenarios have all recently impacted how users utilize computing. Looking forward, Dr. Hsiao-Wuen Hon sees exciting opportunities for research to further extend what is considered natural when using computers. What's natural in computing at the end of 21st century will be drastically different than what we find common today.